Optimal dynamic treatment regimes
نویسنده
چکیده
A dynamic treatment regime is a list of decision rules, one per time interval, for how the level of treatment will be tailored through time to an individual’s changing status.The goal of this paper is to use experimental or observational data to estimate decision regimes that result in a maximal mean response. To explicate our objective and to state the assumptions, we use the potential outcomes model. The method proposed makes smooth parametric assumptions only on quantities that are directly relevant to the goal of estimating the optimal rules. We illustrate the methodology proposed via a small simulation.
منابع مشابه
Dynamic regime marginal structural mean models for estimation of optimal dynamic treatment regimes, Part I: main content.
Dynamic treatment regimes are set rules for sequential decision making based on patient covariate history. Observational studies are well suited for the investigation of the effects of dynamic treatment regimes because of the variability in treatment decisions found in them. This variability exists because different physicians make different decisions in the face of similar patient histories. I...
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